Seems like the honorable thing to do in this case is pull the drug, at least temporarily, from the market. Profit is a powerful force.
The reason is 14 cases of liver failure linked to the drug, including 12 deaths. There is also evidence of increased risk of heart attacks, heart failure, bone fractures, anemia and macular (retinal) edema with vision loss. Safer, more effective drugs for Type 2 diabetes include metformin (sold in Canada under the brand names Glucophag Glumetza or in generic forms with "metformin" as part of the name) and glipizide (brand name Glucotrol), Public Citizen said.
In the statement, Glaxo said it does not believe Avandia causes liver failure and that a review by an independent panel earlier this year said the liver risks were acceptable. The company added heart attack data is inconclusive and that Avandia is safe and effective, when used as directed.
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Avandia outcome is the result of pooled data from a number of trials - none of which were looking specifically at cardiac risks or events, and as the number crunchers did not have access to original source data the outcomes were based on publicly disclosed summaries of events. The government should ban the diabetes drug Avandia because of a wide variety of life-threatening risks, including heart and liver damage, a consumer group said.
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Sally
Promoter
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